gamma-Aminobutyric acid (GABA) induces the acrosome reaction in human spermatozoa
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منابع مشابه
gamma-Aminobutyric acid (GABA) induces the acrosome reaction in human spermatozoa.
The sperm acrosome reaction takes place in response to progesterone and zona pellucida. Progesterone may act on more than one type of surface receptor, of which one is a gamma-aminobutyric acid (GABA) type A-like receptor. Although there is direct evidence of GABA initiation of mouse sperm acrosome reaction, there are conflicting results regarding GABA-induced exocytosis in human spermatozoa. W...
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The acrosome reaction (AR) is influenced by the action of several molecules such as GABA, P 4 , and E 2 . Objective: to determine the interaction between GABA / E 2 , and GABA / P 4 in the AR. Methods: Washed human spermatozoa capacitated for 2 h were incubated in the following conditions: BWW medium alone (control) or BWW plus: P 4, E 2, GABA, GABA+ P 4 or GABA+ E 2. The % of AR was determined...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 1997
ISSN: 1460-2407
DOI: 10.1093/molehr/3.8.677